TraitHigh for tested-variant toxicity risk and CPIC guidance
Chemotherapy (fluoropyrimidine) tolerance (DPYD)
Chemotherapy (fluoropyrimidine) tolerance (DPYD) is a genetic trait Biome reports in its medication response panel: Certain DPYD variants can reduce how quickly your body breaks down 5-FU and capecitabine and raise the chance of severe side effects. A negative tested panel does not rule out risk.
- Category
- Medication response
- Markers
- DPYD activity-score panel including direct HapB3 rs75017182
- Strength of evidence
- High for tested-variant toxicity risk and CPIC guidance
- DNA-test coverage
- Stronger with whole genome
Genes
Markers (rsIDs)
How Biome reads this
Biome's whole-genome test reads this from one saliva sample, alongside all 3.2 billion letters of your DNA.
Biome DNA test →This page is for educational purposes only and is not medical advice. It is not intended to diagnose, treat, cure, or prevent any disease. Genetic results describe tendencies and predispositions, not diagnoses. Always consult a licensed clinician before making decisions about your health, medications, or supplements.