What your DNA reveals

Alcohol flush

Whether drinking alcohol turns your face red, driven by the ALDH2 gene.

ALDH2 rs671

How fast you break down alcohol

How quickly your body breaks down alcohol, set by the ADH1B gene.

ADH1B rs1229984

Lactose tolerance

Whether you likely keep digesting the lactose in milk and dairy as an adult.

MCM6/LCT rs4988235

How fast you clear caffeine

How quickly your body clears caffeine, influenced by the CYP1A2 gene.

CYP1A2 rs762551

Caffeine intake tendency

A small genetic nudge in how much caffeine you tend to consume, via the AHR gene.

AHR rs4410790

Caffeine sensitivity

How strongly you feel caffeine's effects like jitters and sleep disruption, via the ADORA2A gene.

ADORA2A rs5751876

Bitter taste sensitivity

How strongly you perceive bitter compounds like those in coffee, cruciferous vegetables, and tonic water.

TAS2R38 haplotype (rs713598, rs1726866, rs10246939)

Preference for sweet

A small, exploratory genetic lean in how strongly you tend to prefer sweet foods.

Sweet-taste PRS/GWAS when present

How cilantro tastes to you

Whether cilantro tastes soapy to you, linked to the OR6A2 smell receptor.

OR6A2 rs72921001

Smelling asparagus in urine

Whether you can smell the distinctive odor in urine after eating asparagus.

rs4481887

Recognizing an orange scent

How likely you are to correctly identify an orange smell, from a variant near ADCY2.

rs116058752 near ADCY2

Sweet taste sensitivity

How strongly you register sweetness, set partly by a sweet-taste receptor gene.

TAS1R3 rs307355

Bitter-taste sensitivity (salicin)

How strongly you taste salicin-type bitter compounds, set by a TAS2R16 receptor variant.

TAS2R38 haplotype (rs713598, rs1726866, rs10246939)

Pineapple smell identification (OR4A16)

One of two olfactory-receptor variants that influence how easily you identify pineapple by scent.

OR4A16 rs669453

Pineapple smell identification (OR5A2)

A second olfactory-receptor variant (independent of the first) affecting pineapple-scent identification, with a stronger effect in men.

OR4A16 rs669453

Earwax & body odor type

Whether you have wet or dry earwax and more or less body odor, both set by ABCC11.

ABCC11 rs17822931

Freckling tendency

How many freckles you tend to develop, influenced by the IRF4 gene.

IRF4 rs12203592

Eye color

Your likely eye color, from the single biggest-effect pigmentation variant HERC2/OCA2.

HERC2/OCA2 rs12913832

Sneezing in bright light

Whether you're genetically prone to sneezing in bright light — a harmless reflex.

Intergenic, 2q22.3 (near ZEB2) rs10427255

Male-pattern hair loss tendency

One genetic nudge toward male-pattern hair loss, scored for men only.

EDA2R rs1385699

Headache resistance

Whether you carry an ADARB2 variant linked to fewer headaches.

ADARB2 rs7904615

Closest Broad Ancestry Group

The broad reference population your genotype sits closest to on the 1000 Genomes ancestry map.

1000 Genomes PCA marker panel

Nearby Reference Groups

The other reference clusters your genotype sits close to, beyond the single closest match.

1000 Genomes PCA marker panel

Finer Ancestry Group

A more precise reference sub-group nested within your broad ancestry region, shown when the data supports it.

gnomAD v4.1 genetic-ancestry reference panel

Ancestry Read Confidence

How many of the ancestry-panel marker sites were usable in your sample, which sets how confidently the ancestry cards are shown.

Panel overlap QC

Vitamin B12 level

Your genetically typical circulating vitamin B12 level.

FUT2 rs602662

Active B12 delivery

How efficiently B12 is delivered into your cells, separate from total B12.

TCN2 rs1801198

Folate processing (MTHFR)

How efficiently your MTHFR enzyme processes folate, which influences homocysteine levels.

MTHFR rs1801133

Vitamin D status tendency

A GC variant that tilts your baseline vitamin D level via vitamin D-binding protein.

GC (group-specific component / vitamin D-binding protein) rs2282679

Omega-3 conversion (FADS1)

How efficiently your FADS1 enzyme converts plant omega-3 (ALA) into EPA and DHA.

FADS1 rs174537

Vitamin D level

Whether you carry a GC-gene variant linked to lower vitamin D levels.

GC rs115366859; PDE3B, PSMA1, COPB1, CALCB, BMAL1/ARNTL loci

Vitamin A from plants

How well you convert plant beta-carotene into active vitamin A.

BCO1 rs7501331

Vitamin C absorption

Whether you carry a variant that lowers vitamin C transport into cells.

SLC23A1 rs33972313

Selenium level

How your genes lean your circulating selenium level, a little higher or lower.

CBS rs1789953

Blood-calcium set point (CASR)

Whether your calcium-sensing receptor (CASR) variant nudges your blood-calcium set point upward.

CASR rs1801725

Blood calcium via vitamin-D clearance (CYP24A1)

How your CYP24A1 variant, in the vitamin-D breakdown pathway, leans your blood calcium.

CYP24A1 rs1570669

Blood copper level (SELENBP1)

How your SELENBP1 variant leans your circulating blood-copper level.

SELENBP1 rs2769264

Blood copper level (ceruloplasmin gene)

How your variant near the ceruloplasmin (CP) gene leans your circulating blood-copper level.

CP rs35691438

Magnesium level (MUC1 marker)

How your genetics nudge where your blood magnesium tends to sit, from one of the two main magnesium markers.

MUC1/TRIM46 rs4072037

Magnesium level (TRPM6 marker)

A second magnesium marker where most people carry the lower-leaning version.

TRPM6 rs11144134

Zinc level (PPCDC marker)

How your genetics nudge your typical blood zinc, from the lead zinc marker.

PPCDC rs2120019

Zinc level (CA1 marker)

A second zinc marker adding to your blood-zinc tendency.

CA1 rs1532423

Iron level (TMPRSS6 marker)

How your genetics nudge your iron markers, from the main iron-regulation gene.

TMPRSS6 rs855791

Iron level (TF marker)

A second iron marker reflecting iron transport rather than storage.

TF rs3811647

How you metabolize CYP2C19 drugs

How your body processes drugs handled by the CYP2C19 enzyme, such as some antidepressants, acid-reflux PPIs, and the antiplatelet drug clopidogrel.

CYP2C19 diplotype/phenotype

How you metabolize CYP2D6 drugs

How your body processes drugs handled by the CYP2D6 enzyme, including many antidepressants, opioid painkillers like codeine and tramadol, and some beta blockers.

CYP2D6 diplotype/phenotype

How you metabolize CYP2C9 drugs

How your body processes drugs handled by the CYP2C9 enzyme, including NSAIDs, warfarin, and the seizure medicine phenytoin.

CYP2C9 diplotype/phenotype

Warfarin dose sensitivity (VKORC1)

How sensitive you are to the blood thinner warfarin, based on the VKORC1 gene — higher sensitivity usually means a lower dose.

VKORC1 genotype

Statin muscle-symptom risk (SLCO1B1)

How well the SLCO1B1 transporter moves statins out of your bloodstream — lower function raises the chance of statin-related muscle aches.

SLCO1B1 diplotype/phenotype

Statin & urate-drug transport (ABCG2)

How well the ABCG2 transporter moves rosuvastatin and certain urate-lowering drugs — reduced function raises drug levels and is linked to gout risk.

ABCG2 diplotype/phenotype

GLP-1 weight-loss drug response markers

Two research markers linked to how you might respond to GLP-1 weight-loss drugs — one to weight-loss amount (GLP1R), one to nausea on tirzepatide-type drugs (GIPR).

GLP1R rs10305420, GIPR rs1800437

How you metabolize CYP2B6 drugs

How your body processes drugs handled by the CYP2B6 enzyme, most notably the HIV medicine efavirenz.

CYP2B6 diplotype/phenotype

How you metabolize CYP3A5 drugs (e.g. tacrolimus)

Whether you make an active CYP3A5 enzyme, which mainly guides dosing of the transplant drug tacrolimus — expressers often need higher doses.

CYP3A5 diplotype/phenotype

Chemotherapy (fluoropyrimidine) tolerance (DPYD)

How well the DPD enzyme breaks down fluoropyrimidine chemotherapy drugs (5-FU, capecitabine) — lower activity raises the risk of severe side effects.

DPYD phenotype

Thiopurine drug clearance

How quickly your body clears thiopurine drugs such as azathioprine and mercaptopurine, which sets a safe dose.

TPMT diplotype/phenotype

Thiopurine sensitivity

How sensitive you are to thiopurine drugs; reduced-function types risk toxicity and need lower doses.

NUDT15 diplotype/phenotype

Bilirubin & drug clearance (UGT1A1)

How well you process bilirubin and drugs like irinotecan; reduced function underlies Gilbert's syndrome and higher drug toxicity.

UGT1A1 diplotype/phenotype

Anesthesia reaction risk (CACNA1S)

Whether you carry a rare CACNA1S variant linked to a dangerous reaction to certain anesthesia drugs.

CACNA1S diplotype/phenotype

Anesthesia recovery (muscle relaxants)

How fast you clear the anesthesia muscle-relaxant succinylcholine; reduced function can prolong its effect.

BCHE rs1803274, rs1799807

Sleep timing (morning vs evening)

Whether your genes lean you toward being a morning lark or a night owl.

Chronotype/morningness PRS

Insomnia tendency

A modest genetic lean toward difficulty falling or staying asleep.

Insomnia PRS

Natural sleep length

A small genetic lean toward a naturally shorter or longer night's sleep.

Sleep-duration PRS

REM vs deep-sleep balance (MEIS1)

How your MEIS1 variant tilts the balance between REM and deep (NREM) sleep.

MEIS1 rs113851554

Endurance tendency

An exploratory genetic lean in natural aerobic endurance.

Endurance PRS when present

Aerobic capacity

An exploratory genetic lean in your body's aerobic capacity (VO₂ max).

VO2max PRS when present

Genetic activity drive

A very small genetic lean in how inclined you are toward physical activity.

Leisure / occupational / household activity PRS

Tendon & ligament injury tendency

How your collagen (COL5A1) gene leans your tendons and ligaments toward soft-tissue injury.

COL5A1 rs12722

Exercise muscle-energy enzyme (AMPD1)

Whether your muscle AMPD1 energy enzyme works fully, which can affect cramping and fatigue during hard exercise.

AMPD1 rs17602729

Power vs endurance muscle

Whether your ACTN3 gene favors powerful, explosive muscle or endurance.

ACTN3 rs1815739

Endurance training response

How much your aerobic fitness may improve in response to endurance training.

PPARGC1A rs8192678

Sex-hormone transport (SHBG)

A small-effect SHBG variant linked to slightly higher or lower sex-hormone binding globulin.

SHBG rs6259

Estrogen production (aromatase)

How active your aromatase enzyme is, which converts testosterone into estrogen.

CYP19A1 rs10046

Testosterone tendency

A variant linked to slightly higher or lower baseline testosterone, studied mainly in European men.

JMJD1C rs10822184

FOXO3 longevity variant

How many copies you carry of a FOXO3 variant enriched in people who live to very old age.

FOXO3 rs2802292

Antioxidant enzyme (SOD2)

How efficiently your SOD2 antioxidant enzyme reaches the mitochondria where it neutralizes oxidative stress.

SOD2 rs4880

Stress-response gene (FKBP5)

How strongly your cortisol stress-response system reacts, influenced by the FKBP5 gene.

FKBP5 rs1360780

Skin oiliness

A directional genetic lean in how oily or dry your skin tends to run.

RXRA, SOX9, WNT and p53 pathway loci/PRS when present

Collagen strength

Whether a COL1A1 variant leaves your type I collagen at baseline strength or slightly reduced.

COL1A1 rs1800012

Soft-tissue injury tendency

How a COL5A1 variant leans your odds of tendon and ligament soft-tissue injury.

COL5A1 rs12722

IGF-1 level tendency

A modest genetic lean toward higher or lower circulating IGF-1, a growth factor.

IGF1 rs35767

TNF-α inflammatory signalling

Whether you carry the promoter variant linked to slightly higher TNF-α, an inflammatory signalling molecule.

TNF/LTA rs1800629

Skin matrix remodeling

How actively your skin's MMP1 enzyme breaks down and rebuilds collagen.

MMP1 rs1799750

GSTM1 detox enzyme

Whether both copies of the GSTM1 detox gene are deleted (null) or you keep enzyme activity.

GSTM1 whole-gene deletion (null allele)

GSTT1 detox enzyme

Whether both copies of the GSTT1 detox gene are deleted (null) or you keep enzyme activity.

GSTT1 whole-gene deletion (null allele)

Folate processing (MTHFR)

How well your MTHFR enzyme activates folate, which affects homocysteine and B-vitamin needs.

MTHFR rs1801133

Dopamine clearance speed

How quickly your COMT enzyme clears dopamine and related stress chemicals.

COMT rs4680

Neuroplasticity signaling (BDNF)

A BDNF variant that subtly tunes the activity-driven signaling behind learning and plasticity.

BDNF rs6265

Appetite & weight tendency

How your MC4R appetite gene leans your food intake and body-weight set point.

MC4R rs17782313

Appetite & fullness tendency

Whether your genetics lean toward feeling hungrier sooner, from the main appetite gene.

FTO rs9939609

Gut secretor status

Whether your FUT2 gene releases blood-group sugars into your gut and saliva, which helps shape your microbiome.

FUT2 rs601338, LCT rs4988235

Thyroid hormone activation (bloodstream)

How efficiently your D1 enzyme converts thyroid T4 into active T3 in circulation.

DIO1 rs2235544

Thyroid hormone activation (tissue)

How well your D2 enzyme produces active thyroid T3 locally inside tissues.

DIO2 rs225014

Nicotine dependence tendency

A well-replicated CHRNA5 variant tied to heavier smoking and nicotine dependence in people who smoke.

CHRNA5 rs16969968

Uric-acid clearance & gout risk (ABCG2)

How your ABCG2 (Q141K) variant affects uric-acid clearance and your leaning toward gout.

ABCG2 rs2231142

Uric-acid reabsorption & gout risk (GLUT9)

How your GLUT9 transporter variant leans your uric-acid reabsorption and gout risk.

SLC2A9 (GLUT9) rs7442295

Coronary artery disease risk

Your genetic tendency toward coronary artery disease, scored against people of European ancestry.

CAD PRS (PGS000018 metaGRS) + LPA rs3798220/rs10455872, 9p21 rs1333049, PCSK9 rs11591147

Type 2 diabetes risk

Your genetic tendency toward type 2 diabetes, combining a genome-wide score with the single strongest diabetes gene variant (TCF7L2).

T2D PRS (PGS002771) + TCF7L2 rs7903146

Atrial fibrillation risk

Your genetic tendency toward atrial fibrillation, an irregular and often rapid heart rhythm.

AF PRS (PGS000016) + PITX2 rs2200733, ZFHX3 rs7193343, KCNN3 rs13376333

Osteoporosis risk (bone density)

Your genetically estimated bone density, which shapes how prone you are to low bone density and fractures.

Bone-density PRS (PGS000657 gSOS)

Inflammatory bowel disease risk

Your genetic tendency toward inflammatory bowel disease (Crohn's disease and ulcerative colitis).

IBD PRS (PGS004151) + NOD2 rs2066844/rs2066845/rs2066847, IL23R rs11209026 (protective), ATG16L1 rs2241880

Glaucoma risk

Your genetic tendency toward primary open-angle glaucoma, a leading cause of irreversible vision loss.

POAG GRS (PGS002741) + TMCO1 rs4656461, CDKN2B-AS1 rs4977756, SIX1/6 rs10483727

Asthma and allergy risk

Your genetic tendency toward asthma and related allergic conditions.

Asthma PRS (PGS002311) + 17q21 GSDMB/ORMDL3 rs4795399, IL33 rs992969, IL1RL1 rs72823641

Restless legs syndrome risk

A broad genetic lean toward restless legs syndrome; the evidence isn't precise enough for a percentile.

MEIS1, BTBD9, PTPRD (polygenic)

Late-eating blood-sugar response

An MTNR1B variant that shapes how much late-night eating nudges your blood sugar via melatonin signaling.

MTNR1B rs10830963

Anesthesia reaction risk (RYR1)

Whether you carry an RYR1 variant linked to a dangerous reaction to certain anesthesia drugs.

RYR1 diplotype/phenotype

Ivacaftor response (CFTR)

Whether you carry a CFTR variant that responds to the cystic-fibrosis drug ivacaftor.

CFTR diplotype/phenotype

Inherited blood-clot risk

Whether you carry Factor V Leiden or Prothrombin 20210A, two inherited variants that raise the odds of abnormal blood clots.

F5 rs6025 (Factor V Leiden), F2 rs1799963

Inherited iron-overload risk

Whether your HFE gene carries the C282Y/H63D combinations linked to hereditary hemochromatosis (iron overload).

HFE C282Y rs1800562, H63D rs1799945

APOE Alzheimer's-risk type

Your APOE gene type (ε2/ε3/ε4), the strongest common genetic factor in late-onset Alzheimer's risk.

APOE rs429358 + rs7412 (e2/e3/e4)

Inherited Parkinson's-risk variants

Whether you carry LRRK2 G2019S or GBA1 N370S, two well-established genetic risk factors for Parkinson's disease.

LRRK2 G2019S rs34637584, GBA N370S rs76763715

Celiac genetic risk type

Whether you carry the HLA-DQ2/DQ8 immune types found in nearly all celiac disease — most useful for ruling celiac out when absent.

HLA-DQ2/DQ8 tags rs2187668, rs7454108

Fatty-liver genetic tendency

A small two-gene nudge (PNPLA3, TM6SF2) toward fatty liver — context, not a diagnosis.

PNPLA3 rs738409, TM6SF2 rs58542926

Macular degeneration (AMD) risk

Your combined CFH and ARMS2 risk-allele count, the two strongest common genetic factors in age-related macular degeneration.

CFH rs1061170 (Y402H), ARMS2/HTRA1 rs10490924

PCOS genetic tendency

A small three-gene tendency toward polycystic ovary syndrome (PCOS) — context, not a diagnosis.

DENND1A rs10818854, FSHB rs11031006, LHCGR rs13405728