At-home DNA test

You're taking advice meant for someone else's body.

Our at-home DNA test and pharmacogenomic report explain how your body actually processes food, medication, and sleep.

You eat well and buy the good brands. None of it knows whether your body actually uses that vitamin D, clears caffeine by lunch, or needs more sleep than the person beside you. One cheek swab reads the parts of your DNA that settle all of it, then hands you answers you can use this week.

One time

$249

$329

Order your test

Your kit arrives in a few days. Swab, mail it back, and results land in the Biome app about two weeks later. You keep a copy of your DNA data for good.

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Your results, in plain words

CaffeineSlow to clear it
Vitamin DYou likely run low
Omega-3Weak converter
Privacy & security

Your DNA stays yours.

Your DNA isn't ordinary data. It's permanent, it identifies you, and it says something about your family too. So we don't ask you to trust a promise, we chose structure. Our lab partner is a Delaware Public Benefit Corporation, legally bound to keep identifiable genetic data under your control and off the market. It does not, cannot, and will not sell your data.

Processed by CLIA- and CAP-accredited laboratories in the United States.

A Public Benefit Corporation

Our lab partner's purpose is written into its legal charter, not a marketing page. Its directors are bound to weigh your privacy, not only shareholder return, even when selling data would be the more profitable move.

Never for sale

Your individual genetic data is never sold or licensed. Not to researchers, pharmaceutical companies, insurers, or data brokers, and shared with law enforcement only under valid legal process.

Never used to train AI

Identifiable genomic data is never used to train AI models, and de-identified or aggregated genomic datasets are never sold or commercially distributed.

Yours to delete

There's no hidden research program behind your purchase. Your data is delivered to you, access is revocable, and a deletion request removes it rather than archiving it for later.

What you get

No gene names to google.

Most DNA reports read like a lab printout. Rows of letters, numbers, and Latin, and no idea what to do with any of it. Yours reads like a person talking. Each finding says what it means and the one change worth making.

Here's a sample of what lands in your app.

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Sample resultsfrom your DNA

Caffeine

Slow to clear it

Coffee lingers. Keep it before noon.

Vitamin D

You likely run low

Your body makes less from sunlight.

Omega-3

Weak converter

Get it from fish, not flax or seeds.

Training

Built for endurance

You answer better to longer efforts.

Sleep

Night-owl leaning

Your internal clock runs late.

Woman holding a yoga pose

Same coffee. Same dose. A completely different body.

Two people drink the same cup. One is wired until 2am, the other feels nothing. A lot of that gap is written in your genes, right next to the code that decides which vitamins help you and when your body wants to sleep. Most people never get to read it.

Read yours for $249
What you'll learn

Answers you can use tomorrow.

Six areas of your everyday life, read from the spots in your DNA that shape them.

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Food and drink

Whether coffee keeps you up past midnight, how hard alcohol hits, why dairy turns on you, and why cilantro, asparagus, orange, or pineapple smells and tastes different to different people.

Supplements and vitamins

The ones your body uses well, and the ones it barely touches. Vitamin D, B12, folate, omega-3, plus context for how sun, season, supplements, and labs can change the picture.

Sleep

Early bird or night owl, written into your DNA before you ever set an alarm. Plus sleep-duration and sleep-stage context when the covered markers support it.

Training and recovery

Some bodies are built for the sprint, others for the long haul. Find out which one is yours, and how long you really need between hard days.

Medications

How your body tends to handle whole families of common medicine, from antidepressants and pain meds to statin and GLP-1 response context. The kind of thing worth bringing to your doctor, not the group chat.

Traits and resilience

Taste and smell quirks, body traits, and the stress and recovery tendencies you were born with and never picked.

Ancestry reference context

How your DNA compares with public reference groups, shown as broad genetic similarity with a confidence note, not ethnicity or identity.

Order your test$249, one time. Answers in about two weeks.
Every insight

Dozens of insights this test can surface.

Your DNA test reads hundreds of thousands of key spots in your DNA. Here is everything it can surface when those spots are covered. A few areas, medications especially, read more completely from a whole genome.

A DNA test reads a fixed set of spots, so a few of these (mostly polygenic scores) show up only if your sample covers them, and medications read more completely from a whole genome. Everything else is included.

Food & drink

  • Alcohol flush response

    How quickly you clear acetaldehyde, the cause of alcohol flushing.

    ALDH2 rs671

  • Alcohol metabolism

    How fast your body breaks alcohol down.

    ADH1B rs1229984

  • Lactose digestion

    Whether you keep making lactase into adulthood for digesting dairy.

    MCM6/LCT rs4988235

  • Caffeine metabolism

    Whether you tend to clear caffeine quickly or slowly.

    CYP1A2 rs762551

  • Caffeine intake tendency

    Genetics linked to how much caffeine people gravitate toward.

    AHR rs4410790

  • Caffeine sensitivity

    How caffeine tends to affect your sleep and jitters.

    ADORA2A rs5751876

Taste & smell

  • Bitter taste sensitivity

    How strongly you taste bitter compounds (PTC/PROP).

    TAS2R38 haplotype (rs713598, rs1726866, rs10246939)

  • Cilantro perception

    Whether cilantro is more likely to taste soapy to you.

    OR6A2 rs72921001

  • Asparagus odor detection

    Whether you can smell the odor in urine after asparagus.

    rs4481887

  • Orange smell identification

    Genetic context for orange-smell recognition differences.

    rs116058752 near ADCY2

    If covered
  • Pineapple smell identification

    Genetic context for pineapple-smell recognition differences.

    rs669453, rs61902559, OR11H7-region variants

    If covered
  • Sweet preference

    Tendency toward sweet taste and preference.

    Sweet-taste PRS/GWAS when present

    If covered

Body traits

  • Earwax & body odor type

    Wet vs dry earwax and underarm odor precursor production.

    ABCC11 rs17822931

  • Freckling

    Tendency to freckle and pigmentation response to sun.

    IRF4 rs12203592

  • Eye color & pigmentation

    Pigmentation context, including eye color.

    HERC2/OCA2 rs12913832

  • Photic sneeze reflex

    Tendency to sneeze when moving into bright light.

    rs10427255, rs11856995

Ancestry reference context

  • Broad reference cluster

    Which broad public reference cluster your DNA projects closest to, such as European, East Asian, African, South Asian, or Admixed American.

    1000 Genomes PCA marker panel

    If covered
  • Nearby reference groups

    Nearby 1000 Genomes population-label groups, shown as reference similarity rather than ethnicity, nationality, or identity.

    1000 Genomes PCA marker panel

    If covered
  • Marker overlap confidence

    How many ancestry-panel markers were usable, so low-overlap results can be softened or hidden.

    Panel overlap QC

    If covered

Vitamins & nutrients

  • Vitamin D status

    Tendency toward lower circulating vitamin D and how you transport it.

    GC rs4588, GC rs2282679, CYP2R1 rs10741657, DHCR7/NADSYN1 rs12785878

  • Vitamin D sun-response context

    How vitamin D genetics may interact with sun exposure, season, supplements, and lab values.

    GC rs115366859; PDE3B, PSMA1, COPB1, CALCB, BMAL1/ARNTL loci

    If covered
  • Vitamin A conversion

    How well you convert beta-carotene into active vitamin A.

    BCO1 rs7501331

  • Folate pathway

    Folate processing and homocysteine context.

    MTHFR rs1801133, MTHFR rs1801131

  • Vitamin B12

    B12 transport and status context.

    TCN2 rs1801198, FUT2 rs602662

  • Vitamin C transport

    Vitamin C transport tendency.

    SLC23A1 rs33972313

    If covered
  • Omega-3 conversion

    How well you convert plant ALA into EPA and DHA.

    FADS1 rs174537, rs174546, rs174547; FADS2 rs174575

Medication response

  • CYP2C19 substrates

    Processing context for some antidepressants, reflux meds, and antiplatelet drugs.

    CYP2C19 diplotype/phenotype

    Stronger with whole genome
  • CYP2C9 substrates

    Processing context for NSAIDs, warfarin, and phenytoin.

    CYP2C9 diplotype/phenotype

    Stronger with whole genome
  • Warfarin sensitivity

    Warfarin sensitivity context.

    VKORC1 genotype

    Stronger with whole genome
  • Statin muscle symptoms

    Context for statin-related muscle symptoms.

    SLCO1B1 diplotype/phenotype

    Stronger with whole genome
  • Statin and urate-drug transport

    Additional transporter context for some statins and related medications.

    ABCG2 diplotype/phenotype

    Stronger with whole genome
  • GLP-1 medication response context

    Inherited context for GLP-1 weight-loss response or nausea signals, for clinician review only.

    GLP1R rs10305420, GIPR rs1800437

    If covered
  • CYP2B6 substrates

    Efavirenz and other drug metabolism context.

    CYP2B6 diplotype/phenotype

    Stronger with whole genome
  • CYP3A5 substrates

    Tacrolimus and other CYP3A5 substrate context.

    CYP3A5 diplotype/phenotype

    Stronger with whole genome
  • DPYD substrates

    Fluoropyrimidine tolerance context.

    DPYD phenotype

    Stronger with whole genome
  • Thiopurine metabolism (TPMT)

    Thiopurine metabolism context.

    TPMT diplotype/phenotype

    Stronger with whole genome
  • Thiopurine sensitivity (NUDT15)

    Thiopurine sensitivity context.

    NUDT15 diplotype/phenotype

    Stronger with whole genome
  • UGT1A1 substrates

    Irinotecan and bilirubin metabolism context.

    UGT1A1 diplotype/phenotype

    Stronger with whole genome
  • G6PD context

    Oxidative-hemolysis context for certain medications.

    G6PD phenotype

    Stronger with whole genome
  • CACNA1S substrates

    Anesthesia-related malignant hyperthermia susceptibility context for volatile anesthetics and succinylcholine.

    CACNA1S diplotype/phenotype

    Stronger with whole genome
  • RYR1 substrates

    Anesthesia-related malignant hyperthermia susceptibility context for volatile anesthetics and succinylcholine.

    RYR1 diplotype/phenotype

    Stronger with whole genome
  • CFTR substrates

    Ivacaftor responsiveness context for people with cystic fibrosis.

    CFTR diplotype/phenotype

    Stronger with whole genome
  • CYP3A4 substrates

    Quetiapine and other CYP3A4 substrate metabolism context.

    CYP3A4 diplotype/phenotype

    Stronger with whole genome

Sleep & chronotype

  • Morning vs evening tendency

    Whether you lean toward being a morning or evening person.

    Chronotype/morningness PRS

    If covered
  • REM vs NREM sleep architecture

    Genetic context for sleep-stage balance from device-measured sleep research.

    MEIS1 rs113851554, rs4544423, rs182588061; KCNK9 rs888346

    If covered
  • Insomnia tendency

    Genetic context for insomnia tendency.

    Insomnia PRS

    If covered
  • Sleep duration tendency

    Genetic context for typical sleep duration.

    Sleep-duration PRS

    If covered

Fitness & performance

  • Power vs endurance

    Muscle-fiber tendency toward sprint/power or endurance.

    ACTN3 rs1815739

  • Endurance context

    Additional endurance and power context.

    ACE rs4343

  • Aerobic trainability

    Mitochondrial and aerobic-response context.

    PPARGC1A rs8192678

  • Endurance tendency

    Polygenic endurance tendency.

    Endurance PRS when present

    If covered
  • Aerobic capacity (VO2max)

    Polygenic aerobic-capacity tendency.

    VO2max PRS when present

    If covered

Hormone pathways

  • Sex-hormone transport

    Sex-hormone binding globulin context.

    SHBG rs6259

  • Estrogen pathway

    Aromatase and estrogen-pathway context.

    CYP19A1 rs10046

Stress, longevity & antioxidants

  • Longevity-associated marker

    A well-studied longevity-associated marker, for context.

    FOXO3 rs2802292

  • Oxidative-stress pathway

    Antioxidant enzyme and oxidative-stress context.

    SOD2 rs4880

  • Stress-response pathway

    Stress-response and cortisol-signaling pathway context.

    FKBP5 rs1360780

Skin & connective tissue

  • Collagen & connective tissue

    Collagen, tendon, and connective-tissue context.

    COL1A1 rs1800012, COL5A1 rs12722

  • Skin matrix remodeling

    Matrix remodeling and collagen context for skin.

    MMP1 rs1799750

  • Skin oil-gland biology

    Cosmetic skin-context signals tied to pilosebaceous-unit biology, not a dermatology diagnosis.

    RXRA, SOX9, WNT and p53 pathway loci/PRS when present

    If covered
  • Growth & repair axis

    IGF-1 and growth-hormone-axis context.

    IGF1 rs35767, GHR rs6184

  • Inflammatory signaling

    Baseline inflammatory-signaling context.

    IL6 rs1800795, TNF/LTA rs1800629

Cognition & methylation

  • Dopamine & catecholamines

    Dopamine, stress, and estrogen-pathway processing (COMT activity).

    COMT rs4680

  • Neuroplasticity

    BDNF-pathway context for learning and plasticity.

    BDNF rs6265

  • One-carbon / methylation

    Folate and methionine-cycle methylation context.

    MTHFR rs1801133, rs1801131; MTR rs1805087; MTRR rs1801394

Ancestry reference context

Where your DNA sits next to public reference groups.

Your report can compare your DNA with public reference-panel samples and show broad genetic similarity when enough markers are available. It is not an ethnicity test, a nationality label, or a family-origin verdict.

Broad cluster

European, East Asian, African, South Asian, or Admixed American reference-panel similarity.

Nearby labels

Reference groups like Puerto Rican, Iberian, Toscani, British, Yoruba, Bengali, or Han Chinese when the signal supports it.

Confidence

A marker-overlap quality note so limited samples are labeled carefully or not shown.

Example wording: “Your DNA projects closest to the European reference cluster, with nearby reference-panel groups including Iberian and Toscani. This is genetic similarity to public reference samples, not an ethnicity or country-of-origin result.”

Order your testShown only when the marker coverage supports it.
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The science, kept simple

Hundreds of thousands of the spots that actually matter.

Your DNA runs about three billion letters long. Most of them are identical from one person to the next. The interesting part is the small set of spots where we differ, and that's exactly where this test reads, across the well-studied markers tied to nutrition, vitamin D response, sleep, smell and taste, fitness, recovery, and how your body meets common medicine.

It's built for wellness you can act on, not for scaring you. We don't do disease reports. Anything that belongs in front of a doctor, we say so plainly.

Sprinter on a running track

Stop guessing what your body needs. Start reading it.

One swab today. Plain answers in about two weeks. The effort you already put into eating well, training, and sleeping finally points the right direction.

Order your test for $249No needles. No clinic. No subscription.
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From swab to answers in about two weeks.

01

Swab your cheek

The kit shows up in a few days. Thirty seconds with a swab, no needles, no clinic, no fasting.

02

Mail it back

Drop the prepaid kit in the post. Track it the whole way, from your mailbox to our lab.

03

Read your answers

About two weeks later, your results open in the Biome app, written in plain language and ready to act on.

What it can tell you

Everyday tendencies for caffeine, alcohol, dairy, vitamins, omega-3, sleep, smell, taste, and training, read straight from the key spots in your DNA.

How your body tends to handle common medications, which is useful context to bring to a doctor before any decision.

Taste, smell, body traits, skin context, recovery, and the resilience tendencies you inherited.

Broad ancestry reference context when enough ancestry-panel markers are covered, framed as genetic similarity rather than ethnicity.

What it won't

It reads hundreds of thousands of well-studied spots, not every single letter of your DNA.

It doesn't diagnose disease or stand in for a clinical genetic test.

It can't promise how a drug will work, how long you'll live, or what your vitamin and hormone levels are right now.

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Find out what your body actually needs.

One cheek swab. About two weeks. Answers you keep for good, written so you can act on them the same day they land.

Order your DNA test for $249One-time payment. No subscription, ever.
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Want every letter?

The full genome reads all of your DNA. Once, for the rest of your life.

Same plain answers, broader coverage, and one file that keeps turning up new insights as the science grows. You never have to swab again.

See the full genome

These results describe inherited tendencies and medication-response context from the markers we read. They're educational. They are not a diagnosis, a treatment plan, dosing instructions, or a substitute for clinician review. Some results may be worth discussing with your doctor.