rs5751876
rs5751876 is a variant in the ADORA2A gene, which encodes the adenosine A2A receptor that caffeine blocks in the brain to produce its stimulant effects. The C allele has been associated with a blunted anxiogenic and sleep-disrupting response to caffeine, while T-allele carriers, particularly T/T homozygotes, tend to report greater caffeine-induced jitteriness, nervousness, and sleep disruption after evening caffeine intake. It is the marker used here for caffeine sensitivity, describing tendencies toward caffeine's effects on sleep and jitters.
Traits rs5751876 reads
Gene
Reference databases
How Biome reads this
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