TraitHigh for blood-cell toxicity and CPIC guidance
Thiopurine sensitivity
Thiopurine sensitivity is a genetic trait Biome reports in its medication response panel: NUDT15 variants can raise the chance of dangerously low blood counts with azathioprine, mercaptopurine, and thioguanine.
- Category
- Medication response
- Markers
- NUDT15 diplotype and predicted activity
- Strength of evidence
- High for blood-cell toxicity and CPIC guidance
- DNA-test coverage
- Stronger with whole genome
Genes
How Biome reads this
Biome's whole-genome test reads this from one saliva sample, alongside all 3.2 billion letters of your DNA.
Biome DNA test →This page is for educational purposes only and is not medical advice. It is not intended to diagnose, treat, cure, or prevent any disease. Genetic results describe tendencies and predispositions, not diagnoses. Always consult a licensed clinician before making decisions about your health, medications, or supplements.