rs2802292
rs2802292 is a common intronic variant in FOXO3, a forkhead-box transcription factor gene central to cellular stress resistance and insulin/IGF-1 signaling. It is one of the most replicated longevity-associated markers across human populations, with carriers of the protective G allele showing roughly 1.9-fold higher odds of living past age 95, reduced telomere attrition, and higher telomerase activity compared to common-allele homozygotes. It is reported as a well-studied longevity marker for context rather than a predictive or diagnostic measure.
Traits rs2802292 reads
Gene
Reference databases
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