rs174537
rs174537 is a tag SNP near FADS1, the gene encoding delta-5 desaturase, a rate-limiting enzyme that converts dietary linoleic and alpha-linolenic acid into longer-chain polyunsaturated fatty acids such as arachidonic acid and EPA. It is the strongest common variant associated with plasma arachidonic acid levels in GWAS, with the minor allele linked to lower arachidonic acid and EPA, reflecting reduced desaturase activity — consistent with its use as a marker of how efficiently a person converts plant-based ALA toward EPA and DHA.
Traits rs174537 reads
Gene
Reference databases
How Biome reads this
Biome's at-home DNA test reads this directly from one saliva sample, alongside 650,000+ other markers.
Biome DNA test →This page is for educational purposes only and is not medical advice. It is not intended to diagnose, treat, cure, or prevent any disease. Genetic results describe tendencies and predispositions, not diagnoses. Always consult a licensed clinician before making decisions about your health, medications, or supplements.