MTNR1B
MTNR1B encodes melatonin receptor type 1B, a G-protein-coupled receptor expressed on pancreatic beta cells that mediates melatonin's suppression of insulin secretion as part of circadian metabolic regulation. The common variant rs10830963 is one of the most consistently replicated GWAS signals for fasting glucose and type 2 diabetes risk, and it also modulates individual sensitivity to glucose dysregulation from late-night eating.
Traits MTNR1B shapes
Markers (rsIDs)
Reference databases
How Biome reads this
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