JMJD1C
JMJD1C encodes a jumonji-domain-containing histone demethylase that removes methyl marks from histone H3 lysine 9 (H3K9me1/2), acting as a transcriptional coactivator for nuclear hormone receptors, including the androgen receptor. GWAS have linked variants near JMJD1C, such as rs10822184, to circulating testosterone levels, consistent with its role in modulating androgen-receptor-dependent gene transcription.
Traits JMJD1C shapes
Markers (rsIDs)
Reference databases
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