IGF1
IGF1 encodes insulin-like growth factor 1, a peptide hormone produced mainly by the liver in response to growth hormone (GH) stimulation that mediates most of GH's tissue-growth effects by activating the IGF-1 receptor (IGF1R) to drive cell proliferation, protein synthesis, and bone/muscle growth. Variants near IGF1, such as rs35767, are associated with circulating IGF-1 levels and thus with growth, tissue repair, and metabolic signaling capacity along the GH/IGF-1 axis.
Traits IGF1 shapes
Markers (rsIDs)
Reference databases
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