← Glossary
Gene

CA1

CA1 (carbonic anhydrase 1) encodes a zinc-metalloenzyme abundant in red blood cells and gastrointestinal epithelium that catalyzes the reversible hydration of carbon dioxide to bicarbonate and protons, central to CO2 transport and acid-base buffering. Because carbonic anhydrases require zinc as a catalytic cofactor, common CA1-region variants are associated in GWAS with circulating zinc concentration, matching the dataset's zinc-status trait.

Traits CA1 shapes

Markers (rsIDs)

Reference databases

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