← Glossary
Gene

BTBD9

BTBD9 encodes a BTB/POZ-domain-containing protein of incompletely defined molecular function, expressed broadly including in brain tissue. Genome-wide association studies have repeatedly identified BTBD9 as one of the strongest common-variant loci for restless legs syndrome, with risk alleles also associated with lower serum ferritin/iron stores, consistent with its tie to RLS risk in this dataset.

Traits BTBD9 shapes

Reference databases

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This page is for educational purposes only and is not medical advice. It is not intended to diagnose, treat, cure, or prevent any disease. Genetic results describe tendencies and predispositions, not diagnoses. Always consult a licensed clinician before making decisions about your health, medications, or supplements.